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Adapalene is main ingridient of Differin. Adapalene in small concentrations is a moderator of cellular differentiation, keratinization, and inflammatory processes. The exact mode of action of adapalene is unknown. Adapalene is applied topically to the skin, and its absorption into the blood through this medium is very low. Only trace amounts of adapalene have been found in the plasma of chronically treated patients.
This medicine may come with a patient information leaflet. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. Before applying differin, wash the affected area with a mild soap and gently dry. Apply a thin film of medicine to the affected and surrounding area. Rub in gently.
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